When they tried Gleevec, known generically as imatinib, it had little effect on the cells.
当他们尝试着格列卫，通常被称依马替尼，它很少对细胞有作用。More recently Novartis, a Swiss firm, lost a bitter battle in India over patent protection for Gleevec, a profitable cancer drug.
最近在印度，瑞士公司诺华为保护“格列卫”这一种利润极高的抗癌药物的专利权而战，最终输得灰头灰脸。For those who had received standard doses of Gleevec treatment before, adverse reactions of high-dose Gleevec are mild and tolerable.
对于曾接受常规剂量格列卫治疗的患者，大剂量格列卫不良反应轻微、多可耐受。All patients have not received Gleevec's molecular targeted therapy preoperatively or postoperatively.
所有病例术前及术后均未接受格列卫及其他分子靶向治疗。Resistance to Gleevec has developed in some patients, and research continues on new drugs to overcome that resistance.
一些病人出现了对格列卫的抗药性，而且现在依然在研制克服这种抗药性的新药。It is extremely unlikely that drugs which target a single gene like Gleevec will be active against a major fraction of solid tumors.
单一的基因靶向药物如格列卫将对大多数实体肿瘤有效是绝对不可能的。AIM: To explore how Glivec and HMBA affect the cell growth, apoptosis, cell cycle and cyclin protein expression of K562 cells.
目的：研究格列卫和六亚甲基二乙酰胺（HMBA）对K562细胞增殖、凋亡、细胞周期及周期蛋白表达的影响。Objective To study the side effects of given in treatment of advanced gastrointestinal stromal tumor so as to work out the countermeasures.
目的了解格列卫治疗晚期胃肠道间质瘤患者的不良反应，并提出相对应的护理对策。Objective To study the treatment and its possible mechanism of imatinib-induced severe fluid retention in chromic myeloid leukemia(CML).
目的探讨应用伊马替尼（格列卫）治疗慢性粒细胞白血病发生严重水潴留的处理及其可能的发生机制。