Previously, scientists knew of only one gene, called APOE4, which increases the risk of developing the most common form of the disease.
在此之前，科学家只知道一种称为载脂蛋白E4（APOE4）的基因会增加患最普遍老年痴呆症的风险。ApoE is an important component of plasma lipoproteins, and plays significant roles in lipoprotein metabolism.
载脂蛋白E是血浆脂蛋白的重要组成成分，在脂质代谢中发挥着重要的作用。This finding suggests that properly working apolipoproteins may be essential for coping with tiny inhaled particles.
这一调查结果表明，正常运转的载脂蛋白对于对付小型吸入粒子是必不可少的。Recently, the apoE knockout mice have been regarded as one of most popular animal models in expe. . .
近年来，载脂蛋白E基因小鼠已成为动脉粥样硬化相关研究中最受欢迎的动物模型之一。Objective To present a rapid, sensitive and safe procedure for the determination of human apolipoprotein E alleles.
目的介绍一种高效、灵敏、安全的载脂蛋白E等位基因检测法。Apo-AI is a major protein component of plasma high-density lipoproteins, and plays an important role in cholesterol homeostasis.
载脂蛋白AI（APo—AI）是血浆高密度脂蛋白的主要成分，对胆固醇的动态平衡起到重要的作用。This scoring will determine the targets of therapy for reduction of apolipoprotein B-containing lipoproteins.
其危险得分将决定应用何种治疗方法以降低包括血清载脂蛋白B在内的脂蛋白。A string of amino acids on amyloid beta binds to apo E, and this deadly embrace triggers the transformation of amyloid.
β淀粉状蛋白上的一串氨基酸与载脂蛋白E链接，这种致命的包涵体触发了淀粉状蛋白的变形。One big clue that epsilon 4 might be beneficial emerged several years ago, when Han's team scanned the APOEgenes of 78 American soldiers.
发现E4可能有益的一个巨大的线索出现在几年前，当时韩的研究小组扫描了78个美国士兵的载脂蛋白E基因。